About BIOSHARP Paraformaldehyde Universal Tissue Fixative

Overview:

BIOSHARP Paraformaldehyde Universal Tissue Fixative is a high-quality, ready-to-use solution designed for the fixation of biological tissues in histology and pathology applications. Paraformaldehyde is a widely used chemical fixative that helps preserve the structural integrity and cellular morphology of tissues by cross-linking proteins. This universal fixative is suitable for a variety of tissue types, ensuring high-quality preservation for downstream applications such as microscopy, immunohistochemistry, and molecular analysis.

Key Features:

Universal Application:
BIOSHARP Paraformaldehyde Universal Tissue Fixative is effective for a wide range of tissue types, including both animal and plant tissues, making it ideal for diverse research and clinical applications.

High-Quality Preservation:
This fixative preserves tissue architecture and cellular integrity by cross-linking proteins, ensuring that samples retain their structure and can be analyzed accurately.

Ready-to-Use Solution:
The fixative is provided in a ready-to-use form, eliminating the need for preparation and ensuring consistent, reliable results across experiments.

Non-Toxic and Safe:
BIOSHARP Paraformaldehyde Universal Tissue Fixative is carefully formulated to be safe for handling, providing a secure method for tissue preservation without compromising sample integrity.

Compatible with Various Techniques:
The fixative is compatible with a range of techniques, including light microscopy, electron microscopy, immunohistochemistry, and PCR-based analyses.

Applications:

Histology and Pathology:
BIOSHARP Paraformaldehyde Universal Tissue Fixative is widely used in histology and pathology for tissue preservation, ensuring that cellular structures are well-preserved for examination under the microscope.

Immunohistochemistry:
This fixative is commonly used to preserve tissues for immunohistochemical staining, maintaining antigenic sites for accurate detection and analysis.

Microscopy:
Ideal for light microscopy and electron microscopy, it ensures that tissue samples retain their structural integrity for detailed examination.

Molecular Analysis:
Paraformaldehyde is often used in molecular biology applications, such as PCR, to preserve RNA and DNA integrity, allowing for accurate analysis of genetic material.

Packaging:

BIOSHARP Paraformaldehyde Universal Tissue Fixative is available in various packaging sizes to meet the needs of both small-scale research and large-scale clinical applications.

Instructions for Use:

Preparation:
The fixative is ready to use and should be added to fresh tissue samples immediately after collection. Ensure that the tissue is completely immersed in the solution for optimal fixation.

Fixation Time:
The recommended fixation time varies depending on the tissue type and the intended downstream application. For most tissues, fixation times range from 30 minutes to 4 hours at room temperature.

Storage:
Store BIOSHARP Paraformaldehyde Universal Tissue Fixative in a cool, dry place, away from direct sunlight. Once opened, use within the recommended period for best results.

Safety and Handling:

Wear appropriate personal protective equipment (PPE), such as gloves and safety glasses, when handling BIOSHARP Paraformaldehyde Universal Tissue Fixative. Follow standard laboratory safety procedures and consult the Safety Data Sheet (SDS) for detailed safety and handling instructions.

Conclusion:

BIOSHARP Paraformaldehyde Universal Tissue Fixative is an essential tool for tissue preservation in histological, pathological, and molecular biology applications. Its ability to preserve cellular structure and integrity, along with its compatibility with various techniques, makes it an ideal choice for researchers and clinicians. The ready-to-use solution, combined with its non-toxic nature, ensures safe and reliable results for tissue fixation across a wide range of scientific fields.